Historical borrowing in clinical trials can improve precision and operating characteristics. This package supports a hierarchical model and a mixture model to borrow historical control data from other studies to better characterize the control response of the current study. It also quantifies the amount of borrowing through benchmark models (independent and pooled). Some of the methods are discussed by Viele et al. (2013) <doi:10.1002/pst.1589>.
Version: | 1.0.4 |
Depends: | R (≥ 3.5.0) |
Imports: | dplyr, ggplot2, Matrix, posterior, rjags, rlang, stats, tibble, tidyr, tidyselect, utils |
Suggests: | knitr, markdown, rmarkdown, testthat (≥ 3.0.0) |
Published: | 2022-09-13 |
DOI: | 10.32614/CRAN.package.historicalborrow |
Author: | William Michael Landau [aut, cre], Albert Man [rev], Eli Lilly and Company [cph] |
Maintainer: | William Michael Landau <will.landau at gmail.com> |
BugReports: | https://github.com/wlandau/historicalborrow/issues |
License: | MIT + file LICENSE |
URL: | https://wlandau.github.io/historicalborrow/, https://github.com/wlandau/historicalborrow |
NeedsCompilation: | no |
Language: | en-US |
Materials: | README |
CRAN checks: | historicalborrow results |
Reference manual: | historicalborrow.pdf |
Vignettes: |
Methods Usage |
Package source: | historicalborrow_1.0.4.tar.gz |
Windows binaries: | r-devel: historicalborrow_1.0.4.zip, r-release: historicalborrow_1.0.4.zip, r-oldrel: historicalborrow_1.0.4.zip |
macOS binaries: | r-release (arm64): historicalborrow_1.0.4.tgz, r-oldrel (arm64): historicalborrow_1.0.4.tgz, r-release (x86_64): historicalborrow_1.0.4.tgz, r-oldrel (x86_64): historicalborrow_1.0.4.tgz |
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