cases: Stratified Evaluation of Subgroup Classification Accuracy

Project Status: WIP – Initial development is in progress, but there has not yet been a stable, usable release suitable for the public. R build status

cases is an R package to simultaneously assess classification accuracy of multiple classifiers in several subgroups (strata). For instance, it allows to asses the accuracy of multiple candidate (index) diagnostic tests which is often measured with

A widespread goal in diagnostic accuracy studies a so-called co-primary analysis of these two endpoints, i.e. to show a significant benefit (compared to some benchmark) in sensitivity and specificity for at least one of the candidate classifiers. The package implements different methods for multiplicity adjustment for that purpose (e.g. Bonferroni, maxT, pairs bootstrap).


You can install the development version of cases from GitHub with:

# install.packages("remotes")
remotes::install_github('maxwestphal/cases', build_vignettes = TRUE)


A vignette which explains the basic functionality of the cases package can be displayed as follows:

vignette(topic="package_overview", package = "cases")

The following vignette shows an exemplary usage of the package in the context of biomarker assessment and prediction model evaluation:

vignette(topic="example_wdbc", package = "cases")